science IVD QC Reagent · CLSI M02-Aligned

McFarland Standards — Latex-Based, CLSI-Aligned Inoculum Reference

Pro-Lab McFarland Standards are lot-tested to CLSI M02 %T acceptance ranges and ship without hazmat surcharges — so your AST workflow never waits on a supplier quote.

local_shipping Ships non-hazardous, no surcharge — no Fisher account needed
check_circle CLSI M02-Aligned verified_user Non-Hazardous — GHS Not Classified calendar_today 2-Year Shelf Life block No Sodium Azide thermostat Room Temperature Storage

Testimonials coming soon — request from top 3 accounts.

thermostat

Store at 15–30°C — No Cold Chain

Pro-Lab McFarland Standards are stable at room temperature for up to 2 years — no cold pack receiving, no waiting for a refrigerated tube to equilibrate before use.

IFU Rev 2022 08

description

Lot-Tested QC Ranges — CAP/CLIA Ready

Every lot is manufactured and released against tight %T acceptance ranges per CLSI M02 (0.5 standard: 78.5–84 %T). Certificate of Analysis available on request.

IFU Rev 2022 08

eco

GHS Not Classified — No Hazmat Surcharge

Pro-Lab's polystyrene latex formulation carries no GHS signal word, no pictograms, and no H-statements. No sodium azide means no special drain-disposal restrictions.

SDS Rev 3, May 2020

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Order Direct — No Rep, No Quote Required

Order online in 2 minutes. Complete set (PL2350, 0.5–4.0) or individual standards by concentration — published prices, instant checkout, ships from stock.

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Designed for Every Lab Role

Your CLSI-Aligned Inoculum Standard. In Stock. No Quote Required.

Every clinical microbiology lab performing disk diffusion AST needs a reliable 0.5 McFarland Standard. Pro-Lab's latex-based formulation stores at room temperature, ships non-hazardous, and is available direct — no distributor account, no request-a-quote delay. Order the complete set (PL2350, 0.5–4.0) or individual standards by concentration; each lot ships with documented %T acceptance ranges per CLSI M02.

  • check Lot-tested to CLSI M02 %T acceptance ranges — QC documentation ready for CAP/CLIA survey
  • check Room temperature storage (15–30°C) — no cold chain receiving complications
  • check No sodium azide — standard waste disposal, no drain-disposal restriction

Q: We have a Fisher/VWR contract — can we still order?

Yes. McFarland Standards typically fall below the contract-routing threshold ($500 or under at most institutions) — no contract change required. Also available through VWR (cat. # 21762007).

CLSI-Compliant Turbidity Standards. Direct Vendor. Simple Procurement.

Lab directors need two things from a McFarland Standard supplier: defensible QC documentation for accreditation, and reliable availability when the primary distributor goes on backorder. Pro-Lab Direct ships from stock, publishes lot-specific %T acceptance ranges aligned with CLSI M02, and provides SDS and IFU documentation for your regulatory file on demand.

  • check CLSI M02-aligned QC documentation — %T acceptance ranges per lot for accreditation file
  • check Non-hazardous formulation — no GHS pictograms, no H-statements, no hazmat shipping costs
  • check Priced $4.55 below Remel complete set — $390.76 vs. R20421 $395.31

Q: How does Pro-Lab's documentation satisfy CAP/CLIA requirements?

Each lot ships with documented %T acceptance ranges per CLSI M02. IFU and SDS are available for download at any time. Certificate of Analysis available on request for any lot number.

Visual Comparison or Densitometer — Both Methods Covered.

The bench tech using McFarland Standards every shift needs the same thing every time: a clear turbidity endpoint, a tube that hasn't expired, and no surprises. Pro-Lab's latex formulation gives you a consistent suspension — gently invert before use, compare against the density card, done. Two-year shelf life means less mid-shift expiry scrambling.

  • check Density card included — black/white bar visual comparison; no instrument required
  • check Densitometer compatible — calibration procedure included in IFU
  • check 2-year shelf life — less expiry waste, less mid-shift stockout

Q: Can I use this with my densitometer?

Yes. Confirm your densitometer tube format matches the McFarland Standard tube — if different, decant into your routine-use tube before calibration. Clean tube exterior before each reading.

Complete Set & Individual Standards

Order the complete set or individual concentrations. The 0.5 standard is the required inoculum reference for all CLSI M02 and EUCAST disk diffusion protocols.

Best Value PL2350

McFarland Standard Set

0.5, 1.0, 2.0, 3.0, 4.0 — protective carrying case + density card included

$390.76

PL.2300

McFarland Standard 0.5

Required for all CLSI M02 & EUCAST disk diffusion inoculum preparation

$98.13

PL.2301–PL.2304

Individual Standards 1.0–4.0

Used for identification kits and MIC protocols. Each sold separately.

$98.13 each

Technical Specifications

All values sourced from IFU Rev 2022 08 and SDS Rev 3, May 2020.

Complete set SKU PL2350
Individual SKUs PL.2300 (0.5 · $98.13) · PL.2301 (1.0 · $98.13) · PL.2302 (2.0 · $98.13) · PL.2303 (3.0 · $98.13) · PL.2304 (4.0 · $98.13)
Formulation Polystyrene latex particles in buffer solution
Storage temperature 15°C–30°C (room temperature) — do not freeze
Shelf life Up to 2 years from manufacture date
GHS signal word None — GHS Not Classified · No pictograms · No H-statements
Sodium azide None · Standard lab waste disposal · No drain-disposal restriction
Hazmat shipping Not required — not regulated under DOT, IATA, or IMDG
Density card included Yes — black/white bars for visual turbidity comparison
Densitometer compatible Yes — calibration procedure included in IFU
Regulatory alignment CLSI M02 (M02-A10 cited in IFU) · CLSI M100 · EUCAST Disk Diffusion Method
IFU / SDS revision IFU Rev 2022 08 · SDS Rev 3, May 2020

QC %T Acceptance Ranges — Lot Testing

Per CLSI M02. Certificate of Analysis available on request for any lot number. Download IFU Rev 2022 08 →

Standard %T Low %T High Approx. Cell Density
0.578.5841.5 × 10⁸ cells/mL
1.054613.0 × 10⁸ cells/mL
2.035426.0 × 10⁸ cells/mL
3.022289.0 × 10⁸ cells/mL
4.0142012.0 × 10⁸ cells/mL

How to Use McFarland Standards

visibility

Visual Comparison Method

  1. 1Invert McFarland Standard tube gently several times to uniformly suspend latex particles
  2. 2Prepare bacterial suspension from log-phase growth in sterile saline or equivalent medium
  3. 3Hold both tubes against the black-and-white bars on the enclosed density card
  4. 4Equal disappearance or distortion of the black bar confirms matched turbidity

SOURCE: IFU Rev 2022 08, Procedure section

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Densitometer Method

  1. 1Confirm densitometer tube format matches McFarland Standard tube; decant into routine-use tube if different
  2. 2Invert McFarland Standard tube gently; clean tube exterior (fingerprints affect readings)
  3. 3Calibrate densitometer using McFarland Standards
  4. 4Adjust bacterial suspension turbidity to target McFarland value using calibrated densitometer

SOURCE: IFU Rev 2022 08, Densitometer Procedure

warning

Limitations (from IFU)

  • Colored media: Visual comparison method cannot be used — incorrect results will occur. Use densitometer method.
  • Old cultures: Stationary-phase cultures do not produce expected cell counts. Use log-phase growth only.
  • Instrumentation: Only spectrophotometer/densitometer-calibrated comparisons are validated. Do not improvise.

SOURCE: IFU Rev 2022 08, Limitations section

Pro-Lab vs. Remel — Side-by-Side

Prices confirmed on pro-lab-direct.com and fishersci.com. Note: Remel SDS/IFU not yet retrieved — cells marked "Not confirmed" should be verified before publishing competitive advertising.

Feature Pro-Lab (PL2350) Remel (R20421)
Price — Complete Set $390.76 $395.31
Individual pricing Published online Quote-only on Fisher
Purchase method Direct online — no account needed Fisher account required
Sodium azide None (SDS confirmed) Not confirmed — verify Remel SDS
GHS classification Not Classified (non-hazardous) Not confirmed
Range 0.5–4.0 (5 standards) 0.5–4.0 (5 standards)
Density card Yes Yes (plastic case)

Prices confirmed 2026-04-06 · battlecard-remel.md · SOURCE: pro-lab-direct.com; fishersci.com

Frequently Asked Questions

McFarland Standards are latex-based turbidity reference standards used in clinical microbiology labs to calibrate bacterial inoculum density before performing antimicrobial susceptibility testing (AST). The 0.5 McFarland Standard is required by CLSI M02 and EUCAST disk diffusion protocols for inoculum preparation. Pro-Lab's latex formulation stores at room temperature (15–30°C) with a 2-year shelf life — no cold chain required. SOURCE: IFU Rev 2022 08; CLSI M02; EUCAST

No. Pro-Lab McFarland Standards store at 15–30°C (room temperature). Do not freeze. Room-temperature stability eliminates cold-chain receiving and cold storage requirements. SOURCE: IFU Rev 2022 08

Up to 2 years from the date of manufacture. The expiry date is printed on the tube label — discard after the printed date. The 2-year shelf life reduces expiry waste vs. products with shorter stability. SOURCE: IFU Rev 2022 08

No. Pro-Lab's formulation contains polystyrene latex particles in a buffer solution — no sodium azide. Standard laboratory waste disposal applies with no drain-disposal restrictions. SOURCE: SDS Rev 3, May 2020, Section 3

Yes. Each lot is manufactured and released against %T acceptance ranges aligned with CLSI M02 (IFU references CLSI M02-A10). Ranges: 0.5: 78.5–84 %T · 1.0: 54–61 %T · 2.0: 35–42 %T · 3.0: 22–28 %T · 4.0: 14–20 %T. See QC table above. SOURCE: IFU Rev 2022 08

Yes. All Pro-Lab McFarland Standard sets include a density card with black and white bars for visual turbidity comparison. A densitometer is not required when using the visual comparison method — compare the bacterial suspension against the card until the black bar shows equal disappearance. SOURCE: IFU Rev 2022 08

Yes. The IFU includes a densitometer calibration procedure. Confirm the routine-use tube format matches the McFarland Standard tube; if different, decant the standard into the routine-use tube before calibration. Clean tube exteriors before each reading — fingerprints and debris affect the result. SOURCE: IFU Rev 2022 08

Do not use visual comparison with colored or turbid media — the IFU states this will not provide proper contrast and incorrect results will occur. Use the densitometer method in those cases. Also: use log-phase cultures only. Stationary-phase cultures do not produce expected cell counts even with a correct turbidity match. SOURCE: IFU Rev 2022 08, Limitations

Product Documentation & Regulatory Information

Intended Use

"The McFarland Standards are for use as part of a quality control program for adjusting densities of bacterial suspensions that are used for identification and susceptibility testing."

SOURCE: IFU Rev 2022 08, Intended Use section

Safety Data Sheet

GHS ClassificationNot Classified
Signal WordNone required
PictogramsNone required
Sodium AzideNone
DisposalGeneral lab waste
SDS RevisionRev 3, May 2020
Download SDS (PDF) →

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Complete Set $390.76 (PL2350) — ships non-hazardous, no surcharge

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Download IFU

Rev 2022 08 — QC acceptance ranges, procedure, lot testing documentation

Download IFU (PDF)